You have a lot here. I suggest you break it down into topics and make multiple posts so you can get a specific conversation going just on one topic. Otherwise this is going to be a jumbled mess on responses, assuming anyone wants to take a crack at all this.
At a glance in general, I don’t see any issues in doing what you want, but I see that channels, volts, Samples Per second and Bits per sample all are missing. Try adding more specifics to narrow it down and provide focus.
Gerald